The Bullseye Rash is a sort of bacterial disease and the condition is highly infectious. This is caused at least by three species of bacteria which belong to the group of genus Borrelia. This disease can be mostly seen in both Europe and America. This is also known as the tick-borne disease mainly in the Northern Hemisphere. This ailment is caused in human beings due to the infection caused by the bite of the ticks. Some of the early symptoms of the Bullseye Rash include headache, depression, fever and fatigue. It usually occurs in form of a skin rash and it is mainly called the erythema migrans.