DiGeorge syndrome is generally caused by the deletion of a small piece of chromosome. This deletion occurs in the middle of chromosome. The feature of this chromosome varies widely. It may even occur among the members of the same family and it affects many parts of the body. The symptoms of this disease are birth defects such as congenital heart disease, defects in the palate, learning disability, recurrent infection, mild difference in facial features, etc. Infections may also occur in children due to problem in immunity system. People affected with DiGeorge syndrome must start treatment in its initial stage. It may also lead to kidney failure and autoimmune disorders.