Lymphomatoid Granulomatosis

 

It is a neo-plastic disease, also considered as a systemic angio-destructive lympho-proliferative disease. lymphomatoid means lymphoma-like & granulomatosis denotes microscopic character. Mostly characterized by distinct pulmonary movement. It is most commonly found in older patients, and generally affects lungs, skin and central nervous system.Recent data indicate that the disease is an EBV positive B cell proliferation associated with an exuberant T cell reaction. Most patients affected by this condition have defects in cytotoxic T cell function and reduced levels of CD8+ T cells. It is also common in many immunodeficiency states, such as AIDS, Wiskott-Aldrich syndrome and post-transplantation immunodeficiency. No known cure is available.

Related Posts Plugin for WordPress, Blogger...